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Yue-Min Wang Selected Research

(trans)-Isomer 3,4- Dichloro- N- methyl- N- (2- (1- pyrrolidinyl)- cyclohexyl)- benzeneacetamide

1/2016κ-Opioid Receptor Stimulation Improves Endothelial Function via Akt-stimulated NO Production in Hyperlipidemic Rats.
9/2013κ-opioid receptor activation prevents against arrhythmias by preserving Cx43 protein via alleviation of intracellular calcium.
1/2013Vasculoprotective effect of U50,488H in rats exposed to chronic hypoxia: role of Akt-stimulated NO production.
1/2013Κ-opioid receptor stimulation improves endothelial function in hypoxic pulmonary hypertension.
12/2010Antiarrhythmic effect mediated by κ-opioid receptor is associated with Cx43 stabilization.
8/2009Effects of U50,488H on hypoxia pulmonary hypertension and its underlying mechanism.
5/2009Myocardial apoptosis and infarction after ischemia/reperfusion are attenuated by kappa-opioid receptor agonist.
9/2007Cardioprotective and antiarrhythmic effect of U50,488H in ischemia/reperfusion rat heart.
4/2006U50,488H depresses pulmonary pressure in rats subjected to chronic hypoxia.

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Yue-Min Wang Research Topics

Disease

6Ischemia
12/2010 - 08/2006
5Hypoxia (Hypoxemia)
01/2013 - 04/2006
4Myocardial Infarction
01/2017 - 08/2006
4Right Ventricular Hypertrophy
01/2013 - 04/2006
3Neoplasms (Cancer)
12/2014 - 03/2010
3Myocardial Ischemia (Ischemic Heart Diseases)
09/2013 - 12/2006
3Pulmonary Hypertension
01/2013 - 04/2006
3Infarction (Infarctions)
08/2011 - 09/2007
2Prostatic Neoplasms (Prostate Cancer)
08/2014 - 03/2010
2Cardiac Arrhythmias (Arrythmia)
09/2013 - 12/2010
2Reperfusion Injury
01/2012 - 12/2006
1Infections
04/2018
1Left Ventricular Dysfunction
01/2017
1Hyperlipidemias (Hyperlipidemia)
01/2016
1Cardiovascular Diseases (Cardiovascular Disease)
04/2012
1Aortic Valve Disease
04/2012
1Necrosis
05/2009
1Myocardial Stunning (Stunned Myocardium)
10/2007
1Bradycardia
09/2007
1Hyperemia
12/2006

Drug/Important Bio-Agent (IBA)

9(trans)-Isomer 3,4- Dichloro- N- methyl- N- (2- (1- pyrrolidinyl)- cyclohexyl)- benzeneacetamideIBA
01/2016 - 04/2006
5Opioid Receptors (Opioid Receptor)IBA
01/2016 - 12/2010
4kappa Opioid Receptors (kappa Opioid Receptor)IBA
07/2009 - 04/2006
2Glucose (Dextrose)FDA LinkGeneric
08/2014 - 12/2006
2CarbohydratesIBA
08/2014 - 12/2006
2Connexin 43 (Connexin43)IBA
09/2013 - 12/2010
2Proteins (Proteins, Gene)FDA Link
09/2013 - 12/2010
2Oxygen (Dioxygen)IBA
01/2013 - 01/2013
2ResveratrolIBA
01/2012 - 08/2006
2norbinaltorphimineIBA
12/2010 - 05/2009
2Messenger RNA (mRNA)IBA
12/2010 - 03/2010
1Levofloxacin (Levaquin)FDA Link
04/2018
1Cefoxitin (Cefoxitin Sodium)FDA LinkGeneric
04/2018
1Atrial Natriuretic Factor (ANF)IBA
01/2017
1Natriuretic PeptidesIBA
01/2017
1DiureticsIBA
01/2017
1Ligases (Synthetase)IBA
12/2014
1UbiquitinIBA
12/2014
1ElementsIBA
08/2014
1Cytoplasmic and Nuclear Receptors (Nuclear Receptors)IBA
08/2014
1Carrier Proteins (Binding Protein)IBA
08/2014
1Androgen Receptors (Androgen Receptor)IBA
08/2014
1CalciumIBA
09/2013
1Membrane Proteins (Integral Membrane Proteins)IBA
09/2013
1Transcription Factors (Transcription Factor)IBA
04/2012
1triphenyltetrazoliumIBA
08/2011
1Caspase 3 (Caspase-3)IBA
08/2011
1AndrogensIBA
03/2010
1ORALIT (ORS)IBA
07/2009
1DNA (Deoxyribonucleic Acid)IBA
05/2009
1Vascular Endothelial Growth Factor A (Vascular Endothelial Growth Factor)IBA
01/2008
12- (2- (4- (4- nitrobenzyloxy)phenyl)ethyl)isothiourea methanesulfonateIBA
10/2007
11- (3,4- dichlorophenyl)acetyl- 2- (1- pyrrolidinyl)methylpiperidineIBA
09/2007
1Blood Glucose (Blood Sugar)IBA
12/2006
1PotassiumIBA
12/2006
1Insulin (Novolin)FDA Link
12/2006
1Nitric Oxide (Nitrogen Monoxide)FDA Link
08/2006
1AntioxidantsIBA
08/2006
1Malondialdehyde (Propanedial)IBA
08/2006

Therapy/Procedure

3Intravenous Administration
04/2018 - 04/2006